Publications

Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation

Journal of Experimental Medicine 219, e20212405. Publicación CNIO.

Chaves-Pérez A, Santos-de-Frutos K, de la Rosa S, Herranz-Montoya I, Perna C, Djouder N. (2022), 219: e20212405.

Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis.

Journal of Hepatol 76, 850-861. Publicación CNIO.

Garrido A, Kim E, Teijeiro A, Sánchez PS, Gallo R, Nair A, Matamala Montoya M, Perna C, Vicent GP, Muñoz J, Campos-Olivas R, Melms JC, Izar B, Schwabe RF, Djouder N. (2021), S0168: 02294-7.

Inhibition of the IL-17A axis in adipocytes suppresses diet-induced obesity and metabolic disorders in mice.

Nature Metabolism 3, 496-512. Publicación CNIO.

Teijeiro A, Garrido A, Ferre A, Perna C, Djouder N (2021), Apr;3(4):496-512.

Preview. Greehill C (2021). Nature Reviews Endicrinology; 2021 Jul; 17(7):383.

Coxsackievirus B Type 4 Infection in ß Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing

Cell Reports Medicine 1, 100125. Publicación CNIO.

Bernard H, Teijeiro A, Chaves-Pérez A, Perna C, Satish B, Novials A, Wang JP, Djouder N (2020).

URI is required to maintain intestinal architecture during ionizing radiation.

Science 364, pii: eaaq1165. Publicación CNIO.

Chaves-Pérez A, Yilmaz M, Perna C, de la Rosa S, Djouder N (2019).

mTORC1 inactivation promotes colitis-induced colorectal cancer.

Cell Metabolism 27, 118-135. Publicación CNIO.

Brandt M, Grazioso TP, Fawal MA, Tummala KS, Torres-Ruiz R, Rodriguez-Perales S, Perna C , Djouder N (2018).

Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.

Cell Reports; Apr 18;19(3):584-600. (Citation; 115)

Tummala KS, Brandt M, Teijeiro A, Graña O, Schwabe RF, Perna C and Djouder N (2017)

Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms.

Cancer Cell; Aug 8;30(2):290-307.

Burén S, Gomes AL, Fawal MA, Teijeiro A, Yilmaz M, Tummala KS, Perez M, RodriguezJusto M, R, Megias D and Djouder N (2016)

Metabolic Inflammation-Associated IL17A Causes Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma Development.

Cancer Cell; Jul 11; 30(1):161-175. (Citation; 288).

Gomes AL, Teijeiro A, Burén S, Tummala KS, Yilmaz M, Waisman A, Theurillat JP, Perna C and Djouder N (2016)

Preview. Weber A and Heikenwalder M (2016) Cancer Cell; 2016 Jul 11;30(1):15-17

MCRS1 Binds and Couples Rheb to Amino Acid-Dependent mTORC1 Activation

Developmental Cell 2015 Apr 6;33(1):67-81. (Citation; 79).

Fawal MA, Brandt M, and Djouder N (2015)

Inhibition of De Novo NAD+ Synthesis by Oncogenic URI Causes Liver Tumorigenesis through DNA Damage.

Cancer Cell; 2014 Dec 8;26(6):826.

Tummala KS, Gomes AL, Yilmaz M, Graña O, Bakiri L, Ruppen I, Ximénez Embún P, Sheshappanavar V, Rodriguez-Justo M, Pisano D, Wagner EF and Djouder N (2014)

Preview. Mederacke I and Schwaber RF (2014) Cancer Cell; 2014 Dec 8;26(6):777-778. (Citation; 175).

Peer-Reviewed Reviews

The forgotten art of cold therapeutic properties in cancer: a comprehensive historical guide

iScience. 2023. In press.

Grazioso TP and Djouder N (2023)

Dietary interventions and precision nutrition in cancer therapy.

Trends in Molecular Medicine, 2023 In press.

Martínez-Garay C and Djouder N (2023)

A mechanistic view of the use of cold temperature in the treatment of cancer.

iScience, 2023 In press.

Grazioso TP and Djouder N (2023)

Is liver regeneration key in hepatocellular carcinoma development?

Trends in Cancer, 2022. Nov 5:S2405-8033(22)00228-X.

Rigual MDM, Sánchez Sánchez P, Djouder N (2022)

A comprehensive analysis of prefoldins and their implication in cancer.

iScience 2021 Oct 15;24(11):103273.

Herranz-Montoya I, Park S, Djouder N (2021)

Inflammatory and Non-Inflammatory Mechanisms Controlling Cirrhosis Development.

Cancers (Basel). 2021 Oct 9;13(20):5045.

Sánchez PS, Rigual MDM, Djouder N. (2021)

Detection of chromosome instability by interphase FISH in mouse and human tissues

STAR Protocols; Jun 28;2(3):100631.

Torres-Ruiz R, Grazioso TP, Brandt M, Martinez-Lage M, Rodriguez-Perales S, Djouder N. (2021).

When dormancy fuels tumour relapse

Communications Biology; Jun 16;4(1):747.

Santos-de-Frutos K, Djouder N. (2021).

Cirrhosis: A Questioned Risk Factor for Hepatocellular Carcinoma.

Trends in Cancer; Sep 8:S2405-8033(20): 30237-5.

Garrido A, Djouder N (2020).

Diet, Microbiota, and Colorectal Cancer

iScience; 2019 Oct 10;21:168-187.

Grazioso TP, Brandt M, Djouder N (2019).

NAD+ deficits in age-related diseases and cancer.

Trends in Cancer; 2017 Aug;3(8):593-610.

Garrido A and Djouder N (2017)

Book Chapters

2018. Djouder N (2018) Prefoldins: the new chaperones. Djouder, N (ed.)

Advances in Experimental Medicine and Biology. Springer Nature. vol. 1106. ISBN 978-3-030-00736-2.

2018. Chaves-Pérez A, Thompson S, Djouder N (2018).

Roles and Functions of the Unconventional Prefoldin URI, vol. 1106:95-108; Advances in Experimental Medicine and Biology. Springer Nature.

Co-Authored Papers In Collaboration

2021. Pfister D,…, Djouder N,…, Heikenwälder M (2021) NASH limits anti-tumor surveillance in immunotherapy-treated HCC. Nature; 2021. Apr;592(7854):450-456

2020. McGinley AM, …, Djouder N, Mills KHG (2020) Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells. Immunity; 2020 Jan 27. pii: S1074-7613(20)30029-7.

2019. Malehmir M, …, Djouder N,…, Heikenwalder M (2019) Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer. Nature Medicine; 2019 Apr;25(4):641-655.

2018. Youssif C, …, Djouder N, Nebreda AR (2018) Myeloid p38gamma signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis. EMBO Mol Med; 2018 Jul;10(7). pii: e8403.

2011. Theurillat JP, Metzler SC, Henzi N, Djouder N, Helbling M, Zimmermann AK, Jacob F, Soltermann A, Caduff R, Heinzelmann-Schwarz V, Moch H, Krek W (2011) URI Is an Oncogene Amplified in Ovarian Cancer Cells and Required for Their Survival. Cancer Cell; 2011; 19(3):317-32.

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